CD19 Mouse Monoclonal Antibody [Clone ID: SJ25-C1]

Specifications

Product Data
Clone Name	SJ25-C1
Recommend Dilution	Flow Cytometry: 5 μl is the maximum amount of reagent required for 1 x 106 cells. Lesser amounts of antibody may be sufficient and it is recommended that the customer determines the optimum amount of antibody for each application.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Formulation	Label: FITC State: Liquid Ig fraction Stabilizer: highly purified grade of BSA has been added as a stabilizing protein to bring the final protein concentration to 4-5 mg/ml. Preservative: Sodium Azide Absorption emission: 488 nm / 525 nm
Conjugation	FITC
Storage Condition	Store the antibody undiluted at 2-8°C DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	CD19 molecule
Database Link	Entrez Gene 930 Human UniProt ID P15391
Background	CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lamda light chains. It is expressed on approximately 10% of normal human peripheral blood cells and approximately 60% of splenic lymphocytes. It is not expressed on granulocytes, monocytes or T cells as defined by CD3 expression. CD19 defines a pan B antigen which is expressed from the earliest stages of B progenitor development, but is lost on terminal differentiation to plasma cells. It may also be present on some early myeloid progenitors, particularly those of the monoblastic type. The CD19 antigen is expressed on approximately 12% of peripheral blood lymphocytes. It appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen.
Synonyms	Leu-12, B-cell marker
Reference Data

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