Lamp2 Rat Monoclonal Antibody [Clone ID: M3/84]

Specifications

Product Data
Clone Name	M3/84
Applications	FC, IHC, IP, WB
Recommend Dilution	Flow cytometry: 1/50 - 1/100; Use 10 µl of the suggested working dilution to label 10e6 cells in 100 µl; Results may be enhanced using permeabilisation. Immunoprecipitation. Immunohistochemistry on frozen sections.
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Immunogen	Glycoproteins purified from mouse peritoneal macrophage membranes. Spleen cells from immunised Lewis rats were fused with cells of the mouse P3-NSI/1-Ag4-1 myeloma cell line.
Specificity	This antibody recognises CD107b, also known as MAC-3 and LAMP-2.
Formulation	PBS, pH7.4 containing 0.09% Sodium Azide State: Purified State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	lysosomal-associated membrane protein 2
Database Link	Entrez Gene 16784 Mouse UniProt ID P17047
Background	CD107b is a transmembrane glycoprotein that is associated with lysosomal membranes and is primarily expressed on mononuclear phagocytes. Expression of CD107b does vary between cell populations and the molecular weight of CD107b can vary between 92-120kD. Studies suggest that CD107b may be involved in leucocyte adhesion.
Synonyms	LAMP-2, LAMP-2C, LAMPB
Reference Data

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