Interferon alpha (IFN alpha) Mouse Monoclonal Antibody [Clone ID: UMCh3-IFN-a]

Specifications

Product Data
Clone Name	UMCh3-IFN-a
Applications	ELISA, WB
Recommend Dilution	ELISA. Western Blot: this antibody detects a band of approximately 19 kDa.
Reactivity	Chicken
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant chicken Interferon alpha.
Specificity	This antibody recognizes Interferon alpha (chIFN-alpha). This antibody does not cross react with IFN beta or IFN gamma and does not neutralize chIFN-alpha.
Formulation	PBS containing 0.09% Sodium Azide State: Purified State: Liquid purified IgG
Concentration	lot specific
Purification	Affinity chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Background	The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent.
Synonyms	B Cell Interferon, IFN-alpha, IFNA, Interferon-alpha, Leukocyte Interferon, Type I Interferon
Reference Data

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