DC SIGN (CD209) Mouse Monoclonal Antibody [Clone ID: MR-1]

CAT#: SM2219P

DC SIGN (CD209) mouse monoclonal antibody, clone MR-1, Purified

Conjugation: Unconjugated FITC



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CNY 7,538.00


货期*
4周

规格
    • 200 ug

Product images

Specifications

Product Data
Clone Name MR-1
Applications FC, IF
Recommend Dilution Immunofluorescence.
Flow cytometry: 1/50 - 1/100. Use 10 µl of the suggested working dilution to label 10e6 cells in 100 µl.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Immature myeloid monocyte-derived dendritic cells (MDDCs)
Specificity This antibody recognises DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN, CD209),
a 45 kD C-type lectin that binds ICAM-3.
Formulation PBS, pH 7.4, containing 0.09% sodium azide
State: Purified
State: Liquid IgG fraction
Concentration lot specific
Purification Protein G affinity chtromatography
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name CD209 molecule
Background CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DC's in vitro.
CD209 is involved in dendritic cell (DC) migration and the initial interaction between DC's and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DC's.
Synonyms DCSIGN1, DCSIGN, DC-SIGN1, CLEC4L, Dendritic Cell Marker
Note Clone MR-1 is reported to partially block the functional activity of DC-SIGN (see ref. 2).
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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