CD16 (FCGR3A) Mouse Monoclonal Antibody [Clone ID: MEM-154]

CAT#: SM3011F

CD16 (FCGR3A) mouse monoclonal antibody, clone MEM-154, FITC

Conjugation: Unconjugated Biotin FITC



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CNY 3,810.00


货期*
5周

规格
    • 100 Tests

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Specifications

Product Data
Clone Name MEM-154
Applications FC
Recommend Dilution Flow Cytometry: Analysis of Human blood cells using 20 µl reagent / 100 µl of whole blood or 10e6 cells in a suspension.
The content of a vial (2 ml) is sufficient for 100 tests.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Human granulocytes
Specificity The antibody reacts with the epitope on CD16 antigen that residing in proximity to FG loop (probably BC or C'E loop). CD16 is a low affinity receptor for aggregated IgG (FcgRIII antigen). The antibody MEM-154 reacts with CD16+ granulocytes.
Formulation PBS containing 15 mM Sodium Azide as preservative and 0.2% (w/v) high-grade Protease free BSA as a stabilizing agent.
Label: FITC
State: Liquid purified Ig fraction.
Label: Conjugated with Fluorescein isothiocyanate under optimum conditions. The reagent is free of unconjugated
Conjugation FITC
Storage Condition Store the antibody at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Gene Name Fc fragment of IgG receptor IIIa
Background CD16 (FcgRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgRIII is expressed in two forms FcgRIII-A and -B. FcgRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FceRI-g subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgRIII-A is associated, moreover, with FceRI-b subunit. Besides IgG, FceRI-A can be triggered also by oligomeric IgE. FcgRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.
Synonyms FCGR3A, CD16A, FCG3, FCGR3, IGFR3, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc receptor III-2
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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