CD55 / DAF Mouse Monoclonal Antibody [Clone ID: MEM-118]

Specifications

Product Data
Clone Name	MEM-118
Applications	FC
Recommend Dilution	Flow Cytometry: Analysis of Human blood cells using 20 μl reagent/100 μl of whole blood or 106 cells in a suspension.
Reactivity	Human, Primate
Host	Mouse
Clonality	Monoclonal
Immunogen	HPB-ALL human T cell line
Specificity	The antibody recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells; it is weakly present on NK cells.
Formulation	Tris buffered saline (TBS) Label: FITC State: Liquid purified Ig fraction Preservative: 15 mM sodium azide Label: Conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use.
Conjugation	FITC
Storage Condition	Store the antibody undiluted at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Gene Name	CD55 molecule (Cromer blood group)
Database Link	Entrez Gene 1604 Human UniProt ID P08174
Background	CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.
Synonyms	CR; CROM; DAF; TC
Reference Data

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