SOCS3 Mouse Monoclonal Antibody [Clone ID: SO1]

CAT#: SM3145P

SOCS3 mouse monoclonal antibody, clone SO1, Purified



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CNY 3,810.00


货期*
5周

规格
    • 100 ug

Cited in 3 publications.

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Specifications

Product Data
Clone Name SO1
Applications ELISA, IHC, WB
Recommend Dilution ELISA.
Western blot (Reducing conditions):
Positive Control: Use HeLa human cervix carcinoma cell line.
Sample Preparation: Resuspend approx. 50 mil. cells in 1 ml cold lysis buffer (1% laurylmaltoside in 20 mM Tris/Cl, 100 mM NaCl pH 8.2, 50 mM NaF including protease inhibitor cocktail). Incubate 60 min on ice, centrifuge to remove cell debris. Mix lysate with reducing Laemmli SDS-PAGE sample buffer.
This Clone SO1 is reported to work on Paraffin Sections.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full-length SOCS3 protein.
Specificity This antibody SO1 reacts with SOCS3, an intracellular Cytokine Signaling Inhibitor.
Formulation PBS with 15 mM Sodium Azide as preservative, approx. pH 7.4
State: Purified
State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
Concentration lot specific
Purification Affinity Chromatography on Protein A
Conjugation Unconjugated
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name suppressor of cytokine signaling 3
Background SOCS3 (suppressor of cytokine signaling 3), also known as CIS3 (cytokine-inducible SH2 protein 3) is a negative regulator of particular cytokine signaling pathways. SOCS3 is induced by a variety of cytokines and other stimuli, such as erythropoietin, leptin and lipopolysaccharides and inhibits tyrosinkinase activity of JAK kinases, or e.g. JNK phosphorylation. SOCS3 modulates cytokine-mediated and neoplastic-proliferative responses and is involved also in maintaining leukocytes in quiescent state until antigen stimulation.
Synonyms SOCS-3, CIS-3, SSI3, SSI-3
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (3)

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