CD4 Mouse Monoclonal Antibody [Clone ID: CVS4]
CAT#: SM497PS
CD4 mouse monoclonal antibody, clone CVS4, Purified
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CNY 4,796.00
货期*
4周
规格
Cited in 2 publications. |
Specifications
Product Data | |
Clone Name | CVS4 |
Applications | FC, IHC, IP |
Recommend Dilution | Flow cytometry: 1/25-1/200, use 10µl of this working dilution to label 10e6 cells in 100µl. |
Reactivity | Equine |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Equine thymocytes |
Specificity | This anitbody reacts with T-helper cells, it recognises a 58kDa cell surface glycoprotein that is primarily expressed on a subpopulation of equine T lymphocytes and considered to be the equine homologue of human CD4. |
Formulation | Containing 0.09% Sodium azide State: Purified State: Liquid purified IgG |
Concentration | lot specific |
Purification | Affinity chromatography on Protein G from tissue culture supernatant |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Database Link | |
Background | CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase. |
Synonyms | T-cell surface antigen T4/Leu-3 |
Reference Data |
Citations (2)
The use of this Antibodies has been cited in the following citations: |
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Complex interactions between the major and minor envelope proteins of equine arteritis virus determine its tropism for equine CD3+ T lymphocytes and CD14+ monocytes
,Go YY, Zhang J, Timoney PJ, Cook RF, Horohov DW, Balasuriya UB,
J. Virol.
,PubMed ID 20219931
[CD4]
|
A point mutation in a herpesvirus polymerase determines neuropathogenicity
,Goodman LB, Loregian A, Perkins GA, Nugent J, Buckles EL, Mercorelli B, Kydd JH, Paly G, Smith KC, Osterrieder N, Davis-Poynter N,
PLoS Pathog.
,PubMed ID 17997600
[CD4]
|
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