ProDynorphin (PDYN) (1-13) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, R
Recommend Dilution	Radioimmunoassays: 1/5000. Immunohistochemistry on frozen sections: 1/250 - 1/2500.
Reactivity	Guinea Pig, Hamster, Human, Monkey, Porcine, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, YGGFLRRQFKVVT, corresponding to full-length porcine dynorphin B (1-13), conjugated to thyroglobulin.
Specificity	This antibody recognizes Dynorphin B (1-13), a secreted peptide which mimics the effects of opiate drugs.
Formulation	PBS containing 0.09% Sodium Azide and 1% Bovine Serum Albumin State: Serum State: Liquid serum
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Storage in frost free freezers is not recommended. Should this product contain a precipitate microcentrifugation before use is recommended.
Gene Name	prodynorphin
Database Link	Entrez Gene 29190 RatEntrez Gene 5173 Human UniProt ID P01213
Background	Dynorphin is produced in many different parts of the brain, including the hypothalamus, the hippocampus and the spinal cord, and has many different physiological actions, depending upon its site of production. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. As such, it may help some individuals against addiction. Blocking dynorphin may help alleviate depression.
Synonyms	PDYN, DynorphinB, Dynorphin-B, DynB, Dyn-B
Reference Data
Protein Families	Secreted Protein

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