Telomerase reverse transcriptase (TERT) Mouse Monoclonal Antibody [Clone ID: 2D8]

Specifications

Product Data
Clone Name	2D8
Applications	FC, ICC/IF, IHC, WB
Recommend Dilution	Knockdown Validated, Flow Cytometry: 1:50-1:200, Immunocytochemistry/ Immunofluorescence: 1:50-1:200, Western Blot: 1:500-1:1000, Immunohistochemistry: 1:50-1:100, Immunohistochemistry-Paraffin: 1:50-1:100, Immunohistochemistry-Frozen: 1:50-1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full-length recombinant hTERT from insect cells.
Formulation	0.1% sodium azide
Purification	Ascites
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	telomerase reverse transcriptase
Database Link	NP_937983 Entrez Gene 7015 Human UniProt ID O14746
Background	Telomeres are nucleoprotein structures at the ends of eukaryotic chromosomes. They regulate several crucial cellular functions and participate in the control of complex phenotypes, such as aging and cancer. Cell immortalization is strongly associated with the stabilization of telomere length. Therefore, it is suggested that cancer cells achieve immortalization in part through illegitimate activation of telomerase expression. hTERT is the rate-limiting catalytic subunit of telomerase. Telomerase is an enzyme uniquely associated with immortal cell lines and is useful for identifying undifferentiated PSCs.
Synonyms	CMM9; DKCA2; DKCB4; EST2; hEST2; hTRT; PFBMFT1; TCS1; TP2; TRT
Reference Data
Protein Families	Druggable Genome

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