Glucose Transporter GLUT1 (SLC2A1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ChIP, FC, ICC/IF, IHC, WB
Recommend Dilution	Chromatin Immunoprecipitation, Flow Cytometry: 1 ug/ml, Immunohistochemistry-Frozen: 1:200, Western Blot: 1:500, Flow (Intracellular): 1 ug/ml, Immunohistochemistry: 1:200, In vitro assay, Immunocytochemistry/ Immunofluorescence: 1:1000, Immunohistochemistry-Paraffin: 1:200
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide made to an N-terminal region of the human GLUT1 protein (between residues 1-100). [Swiss-Prot #P11166]
Formulation	Tris-glycine, 150mM NaCl and 0.05% sodium azide
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	solute carrier family 2 member 1
Database Link	NP_006507 Entrez Gene 6513 Human UniProt ID P11166
Background	Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are seven types of glucose transport carrier proteins, designated as Glut 1 to 7. Molecular cloning of glucose transporters have identified a family of closely related genes that encodes at least 7 proteins exhibiting high degree of amino acid homology (45% to 65%), all in the molecular weight range of 40 to 60 kDa. Some transporters exhibit dynamic trafficking between intracellular storage sites and plasma membranes in response to various stimuli. In some tissues Glut proteins are asymmetrically distributed between apical and basolateral membranes, as in blood brain barrier and blood testis barriers. GLUT1 is a major glucose transporter in the mammalian blood brain barrier. It is ubiquitous, and is present at high levels in primate erythrocytes and brain endothelial cells.
Synonyms	CSE; DYT9; DYT17; DYT18; EIG12; GLUT; GLUT-1; GLUT1; GLUT1DS; HTLVR; PED; SDCHCN
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways	Adipocytokine signaling pathway, Pathways in cancer, Renal cell carcinoma

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