Nucleophosmin (NPM1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, ICC/IF, IHC, IP, WB
Recommend Dilution	Immunocytochemistry/ Immunofluorescence: 1:50 - 1:100, Immunohistochemistry: 1:50 - 1:100, Immunohistochemistry-Paraffin: 1:50 - 1:100, Flow Cytometry: 1:100, Immunoprecipitation: 1:50, Western Blot: 1:500
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide made to a C-terminal region of human mutant nucleophosmin (exact sequence is within residues 250-298).
Formulation	100 mM glycine, 65 mM Tris, pH 7.0 in 50% glycerol
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	nucleophosmin (nucleolar phosphoprotein B23, numatrin)
Database Link	NP_002511 Entrez Gene 4869 Human UniProt ID P06748
Background	Nucleophosmin (NPM) is a multi-functional protein that is involved in many cellular activities including cell growth, proliferation and transformation. It is frequently overexpressed in solid tumors, and has recently been found to be mutated and aberrantly localized in the cytoplasm of leukaemic blasts in patients with acute myeloid leukemia (AML).
Synonyms	B23; NPM
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency, Transcription Factors

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