p95 NBS1 (NBN) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ChIP, ELISA, FC, ICC/IF, IHC, Immunoblotting, IP, SDS-PAGE, WB
Recommend Dilution	Chromatin Immunoprecipitation (ChIP), In-situ Hybridization, Western Blot: 1:1000, Knockdown Validated, ELISA, Immunohistochemistry: 1:100 - 1:200, Immunohistochemistry-Paraffin: 1:100 - 1:200, SDS-Page, Immunoblotting, Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/ Immunofluorescence: 1:50-1:200, Immunoprecipitation: 3 ul, Knockout Validated
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Human NBS1 protein (betwqeen residues 1-705)
Formulation	Whole antisera and 0.02% sodium azide
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	nibrin
Database Link	NP_002476 Entrez Gene 4683 Human UniProt ID O60934
Background	The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity, thus revealing a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
Synonyms	AT-V1; AT-V2; ATV; NBS; NBS1; P95
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Homologous recombination

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.