GRB2 Rabbit Polyclonal Antibody
CAT#: TA302011
Rabbit Polyclonal Antibody against GRB2 (Y209)
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CNY 6,314.00
CNY 3,080.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 9,998.00
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 1:1000, IHC: 1:10~50 |
Reactivity | Human, Mouse, Rat, Chicken, Xenopus |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | This GRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from human GRB2. |
Formulation | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
Concentration | lot specific |
Purification | This antibody is purified through a protein A column, followed by peptide affinity purification. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 25206 Da |
Gene Name | growth factor receptor bound protein 2 |
Database Link | |
Background | GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. |
Synonyms | ASH; EGFRBP-GRB2; Grb3-3; MST084; MSTP084; NCKAP2 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Acute myeloid leukemia, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Dorso-ventral axis formation, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Focal adhesion, Gap junction, Glioma, GnRH signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pathways in cancer, Prostate cancer, Renal cell carcinoma, T cell receptor signaling pathway |
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