HPS3 Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1:32,000. WB: 1-3µg/ml.
Reactivity	Human, Mouse, Rat, Pig, Cow
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence PYLLYCSRKKPLT, from the C Terminus of the protein sequence according to NP_115759.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	117372 Da
Gene Name	HPS3, biogenesis of lysosomal organelles complex 2 subunit 1
Database Link	NP_115759 Entrez Gene 12807 MouseEntrez Gene 310288 RatEntrez Gene 84343 Human UniProt ID Q969F9
Background	This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage. The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 3. Alternate splice variants exist, but their full length sequence has not been determined.
Synonyms	BLOC2S1; SUTAL
Reference Data

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