PTF1A Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1:32,000. WB: 0.5-1.5µg/ml.
Reactivity	Human, Mouse, Rat, Dog, Zebrafish
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-WTDEKQLKEQN, from the internal region of the protein sequence according to NP_835455.1.
Formulation	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	pancreas specific transcription factor, 1a
Database Link	NP_835455 Entrez Gene 19213 MouseEntrez Gene 117034 RatEntrez Gene 608313 DogEntrez Gene 256297 Human UniProt ID Q7RTS3
Background	This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers. [provided by RefSeq]
Synonyms	bHLHa29; PACA; PAGEN2; PTF1-p48
Reference Data
Protein Families	Embryonic stem cells, ES Cell Differentiation/IPS

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