CHRNB1 Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1-3ug/ml.
Reactivity	Human, Mouse, Rat, Cow
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence C-QEQEDHDALKED, from the internal region of the protein sequence according to NP_000738.2.
Formulation	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	cholinergic receptor nicotinic beta 1 subunit
Database Link	NP_000738 Entrez Gene 11443 MouseEntrez Gene 24261 RatEntrez Gene 1140 Human UniProt ID P11230
Background	The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq]
Synonyms	ACHRB; CHRNB; CMS1D; CMS2A; CMS2C; SCCMS
Reference Data
Protein Families	Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane

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