Dpm1 Goat Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 0.1-0.3ug/ml.
Reactivity	Rat, Mouse
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence PQGRSSRQDKYS-C, from the N-Terminus of the protein sequence according to NP_034202.1.
Formulation	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	dolichol-phosphate (beta-D) mannosyltransferase 1
Database Link	NP_034202 Entrez Gene 296394 RatEntrez Gene 13480 Mouse UniProt ID O70152
Background	Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
Synonyms	CDGIE; MPDS
Reference Data

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