OCLN Rabbit Polyclonal Antibody
CNY 5,808.00
货期*
5周
规格
Cited in 7 publications. |
经常一起买 (3)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommend Dilution | WB: 1 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | OCLN antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human OCLN. The immunogen is located within the last 50 amino acids of OCLN. |
Formulation | PBS containing 0.02% sodium azide. |
Purification | Affinity chromatography purified via peptide column |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | occludin |
Database Link | |
Background | Tight junctions act as a semi-permeable barrier to the transport of ions, solutes, and water and are considered to function as a fence that divides apical and basolateral domains of plasma membranes. Tight junctions coordinate a variety of signaling and trafficking molecules regulating cell differentiation, proliferation, and polarity and contain a number of junctional proteins including Occludin, Claudins, junctional adhesion molecules (JAMs), as well as multiple scaffold proteins. Occludin, the first identified component of tight junction strands, is thought function as a signal transmitter in multiple signaling pathways and can associate with multiple kinases and phosphatases such as PI3-kinase and protein phosphatases 1 and 2A. At least two isoforms of OCLN are known to exist. |
Synonyms | BLCPMG; PPP1R115 |
Reference Data |
Citations (7)
The use of this Antibodies has been cited in the following citations: |
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ZBTB28 inhibits breast cancer by activating IFNAR and dual blocking CD24 and CD47 to enhance macrophages phagocytosis.
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Cellular and molecular life sciences : CMLS
,PubMed ID 35048182
[OCLN]
|
ZBTB28 induces autophagy by regulation of FIP200 and Bcl-XL facilitating cervical cancer cell apoptosis
,Li, L;Gong, Y;Xu, K;Chen, W;Xia, J;Cheng, Z;Li, L;Yu, R;Mu, J;Le, X;Xiang, Q;Peng, W;Tang, J;Xiang, T;,
Journal of experimental & clinical cancer research : CR
,PubMed ID 33931087
[OCLN]
|
ZBTB28 induce autophagy via regulating FIP200 and Bcl-XL to facilitate apoptosis of cervical cancer
,Li, L;Gong, Y;Xu, K;Chen, W;Xia, J;Cheng, Z;Li, L;Yu, R;Mu, J;Le, X;Xiang, Q;Peng, W;Tang, J;Xiang, T;,
Research Square
[OCLN]
|
DNA methylation downregulated ZDHHC1 suppresses tumor growth by altering cellular metabolism and inducing oxidative/ER stress-mediated apoptosis and pyroptosis
,Le, X;Mu, J;Peng, W;Tang, J;Xiang, Q;Tian, S;Feng, Y;He, S;Qiu, Z;Ren, G;Huang, A;Lin, Y;Tao, Q;Xiang, T;,
Theranostics
,PubMed ID 32863941
[OCLN]
|
Senescence-related deterioration of intercellular junctions in the peritoneal mesothelium promotes the transmesothelial invasion of ovarian cancer cells
,Pakuła, M;Witucka, A;Uruski, P;Radziemski, A;Moszyński, R;Szpurek, D;Maksin, K;Woźniak, A;Sajdak, S;Tykarski, A;Mikuła-Pietrasik, J;Książek, K;,
Sci Rep
,PubMed ID 31110245
[OCLN]
|
Effects of shenling baizhu powder herbal formula on intestinal microbiota in high-fat diet-induced NAFLD rats
,Zhang, Y;Tang, K;Deng, Y;Chen, R;Liang, S;Xie, H;He, Y;Chen, Y;Yang, Q;,
Biomed Pharmacother.
,PubMed ID 29710519
[OCLN]
|
The Potential Effect of Chinese Herbal Formula Hongqijiangzhi Fang in Improving NAFLD: Focusing on NLRP3 Inflammasome and Gut Microbiota
,Liang, S;Zhang, Y;Deng, Y;He, Y;Liang, Y;Liang, Z;Chen, Y;Tang, K;Chen, R;Yang, Q;,
Evidence-Based Complementary and Alternative Medicine
,PubMed ID 29675053
[OCLN]
|
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