LIAS Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB:1:500-1:3000
Reactivity	Human, Mouse, Pig, Rat, Xenopus, Zebrafish, Bovine, X. tropicalis
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant fragment contain a sequence corresponding to a region within amino acids 54 and 258 of Lipoic acid synthetase (Uniprot ID#O43766)
Formulation	0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	42 kDa
Gene Name	lipoic acid synthetase
Database Link	NP_919433 Entrez Gene 79464 MouseEntrez Gene 305348 RatEntrez Gene 11019 Human UniProt ID O43766
Background	The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq]
Synonyms	HGCLAS; HUSSY-01; LAS; LIP1; LS; PDHLD
Note	Seq homology of immunogen across species: Mouse (93%), Pig (95%), Rat (93%), Xenopus laevis (86%), Zebrafish (89%), Bovine (96%), Xenopus tropicalis (86%)
Reference Data
Protein Pathways	Lipoic acid metabolism, Metabolic pathways

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