MTAP Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	IHC:1:100-1:1000; WB:1:500-1:3000
Reactivity	Human, Rhesus Monkey, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant fragment corresponding to a region within amino acids 1 and 283 of MTAP (Uniprot ID#Q13126)
Formulation	1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	31 kDa
Gene Name	methylthioadenosine phosphorylase
Database Link	NP_002442 Entrez Gene 66902 MouseEntrez Gene 4507 Human UniProt ID Q13126
Background	This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown. [provided by RefSeq]
Synonyms	BDMF; c86fus; DMSFH; DMSMFH; HEL-249; LGMBF; MSAP
Note	Seq homology of immunogen across species: Rhesus Monkey (100%)
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Cysteine and methionine metabolism, Metabolic pathways

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