RASA3 Rabbit Polyclonal Antibody
CAT#: TA308271
Rabbit polyclonal antibody to RASA3 (RAS p21 protein activator 3)
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CNY 6,281.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB:1:500-1:3000 |
Reactivity | Human, Mouse, Xenopus, Chicken, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region within amino acids 746 and 834 of RASA3 (Uniprot ID#Q14644) |
Formulation | 1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Concentration | lot specific |
Purification | Purified by antigen-affinity chromatography. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 96 kDa |
Gene Name | RAS p21 protein activator 3 |
Database Link | |
Background | The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane. [provided by RefSeq] |
Synonyms | GAP1IP4BP; GAPIII |
Note | Seq homology of immunogen across species: Mouse (87%), Xenopus laevis (93%), Chicken (100%), Bovine (87%) |
Reference Data |
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