PDZK3 (PDZD2) Rabbit Polyclonal Antibody
CAT#: TA308354
Rabbit polyclonal antibody to PDZK3 (PDZ domain containing 2)
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CNY 6,281.00
货期*
5周
规格
经常一起买 (1)
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB:1:500-1:3000 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region within amino acids 1 and 44 of PDZK3 (Uniprot ID#O15018) |
Formulation | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Concentration | lot specific |
Purification | Purified by antigen-affinity chromatography. |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 302 kDa |
Gene Name | PDZ domain containing 2 |
Database Link | |
Background | Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq] |
Synonyms | AIPC; PAPIN; PDZK3; PIN1 |
Note | Seq homology of immunogen across species: Mouse (92%), Rat (92%) |
Reference Data | |
Protein Families | Druggable Genome |
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