MAP4K5 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:1000-1:10000
Reactivity	Human, Mouse, Rat, Bovine
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide contain a sequence corresponding to a region within amino acids 417 and 482 of KHS
Formulation	0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration	lot specific
Purification	Purified by antigen-affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	95 kDa
Gene Name	mitogen-activated protein kinase kinase kinase kinase 5
Database Link	NP_006566 Entrez Gene 399510 MouseEntrez Gene 503027 RatEntrez Gene 11183 Human UniProt ID Q9Y4K4
Background	This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq]
Synonyms	GCKR; KHS; KHS1; MAPKKKK5
Note	Seq homology of immunogen across species: Mouse (94%), Rat (94%), Bovine (94%)
Reference Data
Protein Families	Druggable Genome, Protein Kinase

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