APC Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1:500~1:3000, IHC: 1:50~1:100, ELISA: 1:40000
Reactivity	Human, Mouse, Rat
Modifications	Phospho-specific
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against synthesized phosphopeptide derived from human APC around the phosphorylation site of serine 2054 (K-P-SP-R-L).
Formulation	Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	adenomatous polyposis coli
Database Link	NP_000029 Entrez Gene 11789 MouseEntrez Gene 24205 RatEntrez Gene 324 Human UniProt ID P25054
Synonyms	BTPS2; DP2; DP2.5; DP3; GS; PPP1R46
Note	APC (Phospho-Ser2054) antibody detects endogenous levels of APC only when phosphorylated at serine 2054.
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Basal cell carcinoma, Colorectal cancer, Endometrial cancer, Pathways in cancer, Regulation of actin cytoskeleton, Wnt signaling pathway

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