Myeloperoxidase (MPO) Rabbit Polyclonal Antibody

CAT#: TA319305

Rabbit polyclonal Myeloperoxidase antibody



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CNY 20,681.00


货期*
5周

规格
    • 2 ml

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经常一起买 (4)
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Recombinant protein of human myeloperoxidase (MPO), nuclear gene encoding mitochondrial protein, 20 µg
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Recombinant protein of human myeloperoxidase (MPO), nuclear gene encoding mitochondrial protein, 100 µg
    • 100 ug

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Specifications

Product Data
Applications WB
Recommend Dilution ELISA: 1:5,000 - 1:20,000, WB: 1:500 - 1:5,000, IP: 1:100
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Myeloperoxidase [Human Leukocytes]
Formulation 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Concentration lot specific
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name myeloperoxidase
Synonyms Myeloperoxidase
Note Human myeloperoxidase (MPO) is a dimeric protein composed of two heavy subunits (53 kDa) and two light subunits (15 kDa). Each MPO molecule contains two prosthetic porphyrins which play an important role in the catalytic cycle. Molecular weights for MPO isoforms from pools of normal human samples range from 114,000 to 140,000 daltons reflecting a heterogeneous mixture of isoforms when assayed under non-reducing conditions of SDS-PAGE. Often MPO from a single donor will yield a homogenous preparation reflecting a single isoform. The carbohydrate component of MPO, consisting of mannose, glucose and N-acetylglucosamine residues is 2.5%. MPO is inhibited by azide and other compounds. MPO is stored in primary granules of neutrophils and serves as a bactericidal agent in that MPO catalyzes the production of hypochlorous acid (HOCl), a powerful oxidant. HOCl is derived from chloride ion (Cl-) and hydrogen peroxide (H2O2). In a number of inflammatory situations, MPO is released into the extracellular matrix where its measurement can be used as an indication of neutrophil activation.
Reference Data
Protein Families Druggable Genome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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