APBA1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 0.5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	APBA1 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human APBA1.
Formulation	APBA1 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	APBA1 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	92 kDa
Gene Name	amyloid beta precursor protein binding family A member 1
Database Link	NP_001154 Entrez Gene 83589 RatEntrez Gene 319924 MouseEntrez Gene 320 Human UniProt ID Q02410
Background	APBA1 Antibody: The Amyloid beta 4 (A4) precursor protein-binding family A member 1 (APBA1) is a member of the X11 protein family and a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). APBA1 stabilizes APP and inhibits production of proteolytic APP fragments including the Aβ peptide that is deposited in the brains of Alzheimer's disease patients. It is thought to be involved in signal transduction processes and is a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. APBA1 can also bind to CASK, a multidomain scaffolding protein involved in brain development and synapse formation.
Synonyms	D9S411E; LIN10; MINT1; X11; X11A; X11ALPHA
Reference Data

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