POU3F2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Rabbit polyclonal POU3F2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human POU3F2.
Formulation	POU3F2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	POU3F2 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	49 kDa
Gene Name	POU class 3 homeobox 2
Database Link	NP_005595 Entrez Gene 18992 MouseEntrez Gene 29588 RatEntrez Gene 5454 Human UniProt ID P20265
Background	POU3F2 Antibody: POU3F2, also commonly known as brain-2, is a member of a family of POU domain genes expressed in mouse brain and is thought to be involved in the development of the neocortex and establishment of neural cell lineage. Recent studies suggest that POU3F2 may be involved with the development of neurodegenerative diseases as well as tumor development and proliferation. Along with the neural-lineage-specific transcription factors ASCL1 and MYT1L, POU3F2 can convert fibroblasts to functional neurons in vitro, a form of artificial stem cells termed induced neuronal (iN) cells, suggesting that these cells may be useful in the treatment of neurodegenerative diseases.
Synonyms	brn-2; BRN2; N-Oct3; oct-7; OCT7; OTF-7; OTF7; POUF3
Reference Data
Protein Families	Transcription Factors

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