Sumo 3 (SUMO3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	SUMO3 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of human SUMO3.
Formulation	SUMO3 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	SUMO3 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	small ubiquitin-like modifier 3
Database Link	NP_008867 Entrez Gene 20610 MouseEntrez Gene 499417 RatEntrez Gene 6612 Human UniProt ID P55854
Background	SUMO3 Antibody: Small ubiquitin-like modifiers (SUMOs) are a family of small, related proteins (Sumo-1/2/3/4) that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation, which is a major regulator of protein function in cellular processes such as nuclear transport, transcriptional regulation, apoptosis and protein stability. All SUMO proteins localize to the nucleus and are covalently conjugated, affecting protein structure, function and interactions. SUMO2 and 3 are 96% identical and are more mobile within nucleus relative to SUMO1. Specific functional differences between SUMO1 and SUMO2 and 3 remain to be identified.
Synonyms	SMT3A; Smt3B; SMT3H1; SUMO-3
Reference Data
Protein Families	Druggable Genome

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