ZMYM2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 0. 125 - 0.25 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	ZMYM1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ZMYM1.
Formulation	ZMYM2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	ZMYM2 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	zinc finger MYM-type containing 2
Database Link	NP_932072 Entrez Gene 76007 MouseEntrez Gene 305913 RatEntrez Gene 7750 Human UniProt ID Q9UBW7
Background	ZMYM2 Antibody: Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. As a member of the MYM (myeloproliferative and mental retardation) gene family, ZMYM1 is widely expressed in different tissues in eukaryotes under several forms derived by alternative splicing. While its function remains unknown, the related protein ZMYM2 has been shown to associate with and stabilize the LSD1-CoREST-HDAC1 (LCH) complex of chromatin through its MYM-type zinc fingers, thereby enhancing the transcriptional repression of several genes, suggesting that ZMYM1 may play a similar role.
Synonyms	FIM; MYM; RAMP; SCLL; ZNF198
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors

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