Calcium binding protein 7 (CABP7) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC:4 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	CaBP7 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human CaBP7.
Formulation	CaBP7 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1ug/ul
Purification	CaBP7 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	calcium binding protein 7
Database Link	NP_872333 Entrez Gene 192650 MouseEntrez Gene 360970 RatEntrez Gene 164633 Human UniProt ID Q86V35
Background	CaBP7 Antibody: Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP7 (Calcium-binding protein 7), contains two EF-hand domains for calcium binding and shares 70% homology with CaBP8 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CaBP7 and 8 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.
Synonyms	CALN2
Reference Data
Protein Families	Transmembrane

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