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Prealbumin (TTR) Rabbit Polyclonal Antibody
CAT＃: TA321118S
Anti-TTR Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 50-200 Positive control: Human ovarian cancer Predicted cell location: Secreted |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Full length fusion protein |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | transthyretin |
| Database Link | |
| Background | This gene encodes transthyretin; one of the three prealbumins including alpha-1-antitrypsin; transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid; and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition; affecting predominantly peripheral nerve and/or the heart; and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy; euthyroid hyperthyroxinaemia; amyloidotic vitreous opacities; cardiomyopathy; oculoleptomeningeal amyloidosis; meningocerebrovascular amyloidosis; carpal tunnel syndrome; etc. |
| Synonyms | CTS; CTS1; HEL111; HsT2651; PALB; TBPA |
| Reference Data | |
| Protein Families | ES Cell Differentiation/IPS, Secreted Protein |
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