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CD10 (MME) Rabbit Polyclonal Antibody
CAT＃: TA321228S
Anti-MME Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 4,840.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 500-2000 WB positive control: 293T cells IHC: 25-100 Positive control: Human colon cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide peptide corresponding to a region derived from 519-533 amino acids of human membrane metallo-endopeptidase |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 86 kDa |
| Gene Name | membrane metallo-endopeptidase |
| Database Link | |
| Background | This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype; which represent 85% of cases of ALL. This protein is not restricted to leukemic cells; however; and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney; where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon; enkephalins; substance P; neurotensin; oxytocin; and bradykinin. This gene; which encodes a 100-kD type II transmembrane glycoprotein; exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced; resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.? |
| Synonyms | CALLA; CD10; CMT2T; NEP; SCA43; SFE |
| Reference Data | |
| Protein Families | Druggable Genome, Protease, Transmembrane |
| Protein Pathways | Alzheimer's disease, Hematopoietic cell lineage, Renin-angiotensin system |
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Rabbit anti-MME Polyclonal Antibody
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