DUSP4 Rabbit Polyclonal Antibody

CAT#: TA321339S

Anti-DUSP4 Rabbit Polyclonal Antibody

Size: 25 ul 100 ul



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CNY 800.00

CNY 1,280.00


货期*
2周

规格
    • 25 ul

Product images

经常一起买 (3)
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Recombinant protein of human dual specificity phosphatase 4 (DUSP4), transcript variant 1, 20 µg
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Transient overexpression lysate of dual specificity phosphatase 4 (DUSP4), transcript variant 1
    • 100 ug

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Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB: 500-2000
WB positive control: RAW264.7 cells
IHC: 50-150
Positive control: Human ovarian cancer
Predicted cell location: Cytoplasm, Nucleus
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 197-394 amino acids of human dual specificity phosphatase 4
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 43 kDa
Gene Name dual specificity phosphatase 4
Background The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK; SAPK/JNK; p38); which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases; different tissue distribution and subcellular localization; and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1; ERK2 and JNK; is expressed in a variety of tissues; and is localized in the nucleus. Two alternatively spliced transcript variants; encoding distinct isoforms; have been observed for this gene. In addition; multiple polyadenylation sites have been reported.
Synonyms HVH2; MKP-2; MKP2; TYP
Reference Data
Protein Families Phosphatase
Protein Pathways MAPK signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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