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DAP5 (EIF4G2) Rabbit Polyclonal Antibody
CAT＃: TA321342S
Anti-EIF4G2 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 3,080.00
Specifications
| Product Data | |
| Applications | WB |
| Recommend Dilution | WB: 500-2000 WB positive control: Hela and HepG2 cells |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 796-812 amino acids of Human Eukaryotic translation initiation factor 4 gamma 2 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 102 kDa |
| Gene Name | eukaryotic translation initiation factor 4 gamma 2 |
| Database Link | |
| Background | Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F); which is a cap binding protein complex that consists of three subunits: eIF4A; eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G; in addition; contains a binding site for eIF4E at the N-terminus. Unlike eIF4G; which supports cap-dependent and independent translation; this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. |
| Synonyms | AAG1; DAP5; NAT1; P97 |
| Reference Data | |
| Protein Families | Transcription Factors |
| Protein Pathways | Viral myocarditis |
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