ACTR1A Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1:1000-2000, WB: 1:200-1000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to C terminal 250 amino acids of human ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	43 kDa
Gene Name	ARP1 actin-related protein 1 homolog A, centractin alpha
Database Link	NP_005727 Entrez Gene 54130 MouseEntrez Gene 294010 RatEntrez Gene 10121 Human UniProt ID P61163
Background	This gene encodes a 42.6 kD subunit of dynactin; a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions; including ER-to-Golgi transport; the centripetal movement of lysosomes and endosomes; spindle formation; chromosome movement; nuclear positioning; and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule; and is the most abundant molecule in the dynactin complex. It is an actin-related protein; and is approximately 60% identical at the amino acid level to conventional actin.
Synonyms	ARP1; Arp1A; CTRN1
Reference Data

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