PSMD14 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: 293T, SKOV3, NIH/3T3 and 231 cells IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm, Nucleus
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 216-310 amino acids of human proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	35 kDa
Gene Name	proteasome 26S subunit, non-ATPase 14
Database Link	NP_005796 Entrez Gene 59029 MouseEntrez Gene 10213 Human UniProt ID O00487
Background	This gene encodes a component of the 26S proteasome. The 26S proteasome is a large multiprotein complex that catalyzes the degradation of ubiquitinated intracellular proteins. The encoded protein is a component of the 19S regulatory cap complex of the 26S proteasome and mediates substrate deubiquitination. A pseudogene of this gene is also located on the long arm of chromosome 2.
Synonyms	PAD1; POH1; RPN11
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Proteasome

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