MIDN Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 500-2000 WB positive control: Human lung tissue
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 2-19 amino acids of Human midnolin
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	49 kDa
Gene Name	midnolin
Database Link	NP_796375 Entrez Gene 59090 MouseEntrez Gene 90007 Human UniProt ID Q504T8
Background	Expression of the?midnolin?gene is developmentally regulated: it is strongly expressed at the mesencephalon (midbrain) of the embryo in day 12.5 (E12.5) mice. The?midnolin?encodes a protein of 508 amino acids (aa); which contains a Ubiquitin-like domain. The intracellular distribution of the?midnolin?was studied by using?midnolin-green fluorescent protein (GFP) fusion proteins.?Midnolin?was found to be localized in the nucleus and nucleolus; but not in the cytoplasm. The nucleolar localization signal was determined to be a 28aa peptide located at the C-terminal region of the?midnolin.?May be involved in regulation of genes related to neurogenesis in the nucleolus
Synonyms	DKFZp547M072
Reference Data
Protein Families	Druggable Genome

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