United States
Germany
Japan
United Kingdom
China
PAK5 Rabbit Polyclonal Antibody
CAT＃: TA322264S
Anti-PAK7 Rabbit Polyclonal Antibody
Size: 100 ul
Need it in bulk or conjugated?
Get a free quote
CNY 800.00
CNY 1,280.00
Product images
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 4,840.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 15-50 Positive control: Human breast cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to C terminal 300 amino acids of human p21 protein (Cdc42/Rac)-activated kinase 7 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | p21 (RAC1) activated kinase 7 |
| Database Link | |
| Background | The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases; which have been implicated in the regulation of cytoskeletal dynamics; proliferation; and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif; and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth; and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. |
| Synonyms | PAK5 |
| Reference Data | |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Axon guidance, ErbB signaling pathway, Focal adhesion, Regulation of actin cytoskeleton, Renal cell carcinoma, T cell receptor signaling pathway |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
| 抗体相关资料 |
