ATPase Inhibitory Factor 1 (ATPIF1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1000-5000 WB positive control: Hela, Jurkat, MCF7 and A431 cells IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 26-106 amino acids of human ATPase inhibitory factor 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	12 kDa
Gene Name	ATPase inhibitory factor 1
Database Link	NP_057395 Entrez Gene 93974 Human UniProt ID Q9UII2
Background	ATPase inhibitor; mitochondrial?is an?enzyme?that in humans is encoded by the?ATPIF1?gene. This gene encodes a mitochondrial ATPase inhibitor. Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified. It prevents ATPase from switching to ATP hydrolysis during collapse of the electrochemical gradient; for example during oxygen deprivation ATP synthase inhibitor forms a one to one complex with the F1 ATPase; possibly by binding at the alpha-beta interface. It is thought to inhibit ATP synthesis by preventing the release of ATP. The inhibitor has two oligomeric states; dimer (the active state) and tetramer.
Synonyms	ATPI; ATPIP; IP
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.