VGLL1 Rabbit Polyclonal Antibody

CAT#: TA322329

Anti-VGLL1 Rabbit Polyclonal Antibody

Size: 25 ul 100 ul



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CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

Cited in 1 publication.

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Specifications

Product Data
Applications WB
Recommend Dilution WB: 2000-10000
WB positive control: 293T cells
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 62-75 amino acids of human vestigial like 1 (Drosophila)
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 29 kDa
Gene Name vestigial like family member 1
Background The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs. TDU interacted directly with the TEA domain family member; TEF1; and deletion of the Vg homology region abolished the interaction. The TDU-TEF1 dimer activated a reporter plasmid; and expression of TDU in Drosophila rescued loss of Vg function. The interaction was stronger in cardiac myocytes; suggesting a myocyte-specific factor may participate in the interaction. Vgll1 was weakly active in driving expression of a reporter gene from the mouse skeletal muscle alpha-actin promoter; and Vgll1 could partially reverse the inhibitory effect of TEF1 in this assay.
Synonyms TDU; VGL1
Reference Data
Protein Families Transcription Factors
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

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