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JAB1 (COPS5) Rabbit Polyclonal Antibody
CAT＃: TA322462S
Anti-COPS5 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 3,080.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 1000-5000 WB positive control: Mouse liver tissue IHC: 150-500 Positive control: Human colon cancer Predicted cell location: Cytoplasm, Nucleus |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Full length fusion protein |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 38 kDa |
| Gene Name | COP9 signalosome subunit 5 |
| Database Link | |
| Background | The protein encoded by this gene is one of the eight subunits of COP9 signalosome; a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors |
| Synonyms | CSN5; JAB1; MOV-34; SGN5 |
| Reference Data | |
| Protein Families | Druggable Genome, Protease, Transcription Factors |
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Rabbit anti-COPS5 Polyclonal Antibody
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