Neurotrophin 4 (NTF4) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: 231 cells IHC: 10-50 Positive control: Human colon cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 25-210 amino acids of human neurotrophin 4
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	22 kDa
Gene Name	neurotrophin 4
Database Link	NP_006170 Entrez Gene 25730 RatEntrez Gene 4909 Human UniProt ID P34130
Background	This gene is a member of a family of neurotrophic factors; neurotrophins; that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor; brain-derived neurotrophic factor; and neurotrophin 3 prove lethal during early postnatal development; NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.
Synonyms	5; GLC1O; GLC10; NT-4; NT-5; NT4; NT5; NTF5
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	MAPK signaling pathway, Neurotrophin signaling pathway

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