Gastric Mucin (MUC6) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 1901-1915 amino acids of Human mucin 6, oligomeric mucus/gel-forming
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	mucin 6, oligomeric mucus/gel-forming
Database Link	NP_005952 Entrez Gene 4588 Human UniProt ID Q6W4X9
Background	The MUC6 gene encodes gastric mucin; a secreted glycoprotein that plays an essential role in epithelial cytoprotection from acid; proteases; pathogenic microorganisms; and mechanical trauma in the gastrointestinal tract. May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis.
Synonyms	MUC-6
Reference Data
Protein Families	Druggable Genome

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