JAK2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 10-50 Positive control: Human lung cancer Predicted cell location: Cytoplasm
Reactivity	Human, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide peptide corresponding to a region derived from 1118-1132 amino acids of human Janus kinase 2
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	Janus kinase 2
Database Link	NP_004963 Entrez Gene 24514 RatEntrez Gene 3717 Human UniProt ID O60674
Background	This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
Synonyms	JTK10; THCYT3
Reference Data
Protein Families	Druggable Genome, Protein Kinase
Protein Pathways	Adipocytokine signaling pathway, Chemokine signaling pathway, Jak-STAT signaling pathway

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