TRF1 (TERF1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: A549 cell lysate IHC: 25-100 Positive control: Human lung cancer Predicted cell location: Cytoplasm and Nucleus
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 63-268 amino acids of human telomeric repeat binding factor (NIMA-interacting) 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	50 kDa
Gene Name	telomeric repeat binding factor 1
Database Link	NP_003209 Entrez Gene 21749 MouseEntrez Gene 7013 Human UniProt ID P54274
Background	This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.
Synonyms	hTRF1-AS; PIN2; t-TRF1; TRBF1; TRF; TRF1
Reference Data
Protein Families	Transcription Factors

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