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VEGF Receptor 1 (FLT1) Rabbit Polyclonal Antibody
CAT＃: TA323071S
Anti-FLT1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
Specifications
| Product Data | |
| Applications | IF |
| Recommend Dilution | IF: 100-500 Positive control: HepG2 cell Predicted cell location: Cytoplasm, Cell membrane |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 1303-1316 amino acids of human fms-related tyrosine kinase 1 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | fms related tyrosine kinase 1 |
| Database Link | |
| Background | This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains; a transmembrane segment; and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A; VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells; placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened; soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia. |
| Synonyms | FLT; FLT-1; VEGFR-1; VEGFR1 |
| Reference Data | |
| Protein Families | Druggable Genome, Protein Kinase, Secreted Protein |
| Protein Pathways | Cytokine-cytokine receptor interaction, Endocytosis, Focal adhesion |
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