CELSR2 Rabbit Polyclonal Antibody
CAT#: TA323174S
Anti-CELSR2 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
CNY 300.00
CNY 1,430.00
CNY 4,140.00
Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm, Cell membrane |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region derived from 2623-2639 amino acids of human cadherin, EGF LAG seven-pass G-type receptor 2 |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | cadherin EGF LAG seven-pass G-type receptor 2 |
Database Link | |
Background | The protein encoded by this gene is a member of the flamingo subfamily; part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains; seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains; a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication; with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined. |
Synonyms | ADGRC2; CDHF10; EGFL2; Flamingo1; MEGF3 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
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