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ABHD12 Rabbit Polyclonal Antibody
CAT＃: TA323295S
Anti-ABHD12 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 25-100 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 96-398 amino acids of human abhydrolase domain containing 12 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | abhydrolase domain containing 12 |
| Database Link | |
| Background | This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG); the main endocannabinoid lipid transmitter that acts on cannabinoid receptors; CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes; including neurotransmission; mood; appetite; pain appreciation; addiction behavior; and inflammation. Mutations in this gene are associated with the neurodegenerative disease; PHARC (polyneuropathy; hearing loss; ataxia; retinitis pigmentosa; and cataract); resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. |
| Synonyms | ABHD12A; BEM46L2; C20orf22; dJ965G21.2; PHARC |
| Reference Data | |
| Protein Families | Protease, Transmembrane |
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