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Glutathione Reductase (GSR) Rabbit Polyclonal Antibody
CAT＃: TA323577S
Anti-GSR Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 1000-5000 WB positive control: Jurkat, Hela and A549 cells IHC: 50-200 Positive control: Human cervical cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 274-475 amino acids of human glutathione reductase |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 56 kDa |
| Gene Name | glutathione reductase |
| Database Link | |
| Background | This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense; and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH; which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. |
| Synonyms | HEL-75 |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Glutathione metabolism |
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